Fab Antibody Fragments: Advantages, Applications, and Limitations Fab antibody fragments are widely used in antibody engineering, therapeutics, and diagnostics because they retain antigen-binding activity while removing the Fc region of full-length IgG. At approximately 50 kDa, Fab fragments offer a useful balance between structural stability, tissue penetration, and production flexibility. Compared with IgG, scFv, and …
Fab Antibody Fragments: Advantages, Applications, and Limitations
