Downstream Purification Strategies for High-Quality VHH Antibody Production

1 Antibody

Downstream Purification Strategies for High-Quality VHH Antibody Production Introduction VHH antibodies, also known as nanobodies, are the smallest antibody fragments (~12–15 kDa) and have gained increasing attention due to their compact size, high stability, and ability to access unique epitopes. Following VHH discovery and VHH phage display screening, successful candidates require optimized expression and purification …